Salidroside Manufacturers thiab lwm tus neeg
Salidrosideyog cov tseem ceeb active ingredient ntawm Rhodiola rosea, ib tsob nroj pom nyob rau hauv siab -altitude cheeb tsam, thiab yog lub npe hu ua ib tug siab -altitude acclimatization tus neeg saib xyuas. Nws muaj cov txiaj ntsig tseem ceeb los tiv thaiv- qaug zog, txhim kho lub cev kev ua haujlwm, ua kom cov lactic acid tshem tawm, thiab txhawb nqa lub cev rov qab. Nws cov khoom muaj zog adaptogenic pab lub cev tiv taus qhov siab, kev ntxhov siab, thiab lwm yam kev ntxhov siab.Noj qab haus huv®yog tus tsim thiab xa khoom ntawm Salidroside. Peb muab 98% Salidroside. Peb muaj ib tug loj -scale ntau lawm cog thiab ib tug kws R & D pab neeg, ua rau peb muab kev pab customized. Yog tias koj xav tau Salidroside hmoov, thov koj xav dawbtiv tauj pebntawminfo@kintaibio.com.
| Khoom npe | Specification | Txoj Kev Xeem |
| Salidroside | Fermentative synthesis | HPLC |
Yuav ua li cas ua Salidroside Hmoov?
Covkev tsim cov salidrosidedhaufermentation synthesispib nrog kev tsim kho ntawm cov noob caj noob ces, nyob rau hauv uas cov enzyme tseem ceeb ARO10 thiab glycosyltransferase tau nkag mus rau hauv E. coli party thiab nws cov txheej txheem metabolic tau ua kom zoo los tsim kom muaj lub Hoobkas ua haujlwm zoo;
Tom qab ntawd cov tshuab tsim hluav taws xob tau qhib thiab coj mus kuaj hauv cov raj xa dej lossis co cov dej kom tau txais cov kab mob txaus kom muaj cov tshuaj tua kab mob zoo li cov noob fermentation, uas yog tom qab inoculated rau hauv lub fermenter rau nplai - nce kab lis kev cai raws li qhov kub thiab txias, pH, thiab yaj cov pa oxygen; Thaum lub cell ceev nce mus txog lub hom phiaj, ib qho inducer xws li IPTG tau ntxiv los ua rau kev nthuav tawm ntawm cov noob exogenous thiab pib loj -scale salidroside synthesis, thaum lub sij hawm cov pa roj carbon zoo li qabzib tau txuas ntxiv mus thiab tsis muaj xws li kub, yaj oxygen, thiab pH raug tswj hwm,;
Thaum kawg,salidrosideyog muab rho tawm thiab purified los ntawm fermentation broth kom tau cov khoom kawg.
Physicochemical Properties ntawm Salidroside
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Khoom |
Kev piav qhia |
|
Tshuaj npe |
2-(4-Hydroxyphenyl)ethyl - -D-glucopyranoside |
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CAS Nr |
10338-51-9 |
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Molecular Formula |
C₁₄H₂₀O₇ |
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Molecular Luj |
300.30 g / mol |
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Qhov tshwm sim |
Dawb rau tawm -dawb crystalline hmoov |
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Melting Point |
Kwv yees li 158℃- 162 degree |
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Solubility |
Dej: Soluble |
|
Kev hloov kho qhov muag |
[ ]²⁵D: -33℃rau -38℃(c=1.0 hauv Methanol) |
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Kev ruaj ntseg |
Nyob ruaj khov nyob rau hauv kev pom zoo cia tej yam kev mob (txias, qhuav qhov chaw). rhiab heev rau ntev raug rau lub teeb muaj zog, kub kub, thiab oxidative tej yam kev mob. |
|
Glycoside Ntuj |
Hydrolyzable los ntawm cov kua qaub uas muaj zog lossis cov enzymes tshwj xeeb ( -glucosidase) rau hauv nws cov aglycone (tyrosol) thiab qabzib. |
Salidroside Mechanism of Action yog dab tsi?
Nws txoj haujlwm tseem ceeb yog txuas mus rau kev ua kom cov xovtooj ntawm tes tseem ceeb, tshwj xeeb yog Akt thiab Nrf2 txoj hauv kev. Los ntawm kev qhib Akt,salidrosidetxhawb txoj kev ciaj sia ntawm tes, lub zog metabolism, thiab kev ua haujlwm mitochondrial, uas ua rau nws tiv thaiv - qaug zog thiab kev tiv thaiv neuroprotective. Ib txhij, nws qhib txoj hauv kev Nrf2 antioxidant, ua rau kev txhim kho ntawm kev tiv thaiv enzymes xws li heme oxygenase-1 (HO-1), yog li tiv thaiv oxidative kev nyuaj siab.
Tsis tas li ntawd, nws qhia tau hais tias tseem ceeb los tiv thaiv- kev ua ub no los ntawm kev tawm tsam NF-κB txoj hauv kev, txo qis kev tsim cov pro- inflammatory cytokines. Nws kuj cuam tshuam cov neurotransmitters tseem ceeb hauv lub hlwb, xws li serotonin thiab dopamine, pab txhawb rau nws cov tshuaj tiv thaiv kev nyuaj siab thiab kev hloov pauv cov khoom. Nyob rau hauv qhov tseeb, salidroside ua raws li ntau- tus neeg sawv cev, txhim kho cellular resilience rau kev ntxhov siab, o, thiab oxidative puas tsuaj.
salidroside vs rosavin, uas zoo dua?
Salidroside thiab rosavinyog ob qho tseem ceeb ntawm cov khoom tseem ceeb ntawm Rhodiola, tab sis lawv txawv heev hauv kev faib tshuaj, kev faib tawm, thiab cov tshuaj pharmacological. Salidroside yog phenylethanoid glycoside pom dav thoob plaws ntau hom Rhodiola, whereas rosavin yog ib qho phenylpropanoid compound feem ntau pom nyob rau hauv cov qhabnias hom rosavin; Yog li ntawd, salidroside ua hauj lwm raws li ib tug general marker rau Rhodiola genus, thaum rosavin ua raws li ib tug tshwj xeeb cim rau rosavin.
Hais txog kev ua lag luam tshuaj, ob lub tebchaw muaj tshuaj tiv thaiv- qaug zog, tshuaj tiv thaiv kev nyuaj siab, thiab cov tshuaj tiv thaiv kab mob immunomodulatory. Txawm li cas los xij, salidroside yog qhov zoo tshaj plaws rau rosavin nyob rau hauv cov nqe lus ntawm qhov ncauj nqus thiab bioavailability; nws muaj peev xwm hla cov ntshav- lub paj hlwb teeb meem thiab nyiam faib rau hauv nruab nrab paj hlwb, whereas rosavin muaj tsawg qhov ncauj bioavailability thiab tsis muaj pov thawj ncaj qha ntawm lub hlwb nkag mus. Hauv kev tiv thaiv- kev soj ntsuam qaug zog, salidroside ua tau zoo me ntsis zoo dua li rosavin ntawm cov koob tshuaj sib npaug, thiab lawv cov txiaj ntsig zoo sib piv ntawm cov koob tshuaj siab, txawm hais tias rosavin tuaj yeem ua rau muaj kev cuam tshuam tshwj xeeb hauv qee cov ntsiab lus tshwj xeeb.
Cov txiaj ntsig ntawm Salidroside yog dab tsi?
Salidroside rau lub hlwb
Salidroside muaj ntau yam kev tiv thaiv thiab kho kom zoo rau lub hlwb. Muaj peev xwm hla cov ntshav- lub hlwb thaiv kom nkag mus rau hauv nruab nrab lub paj hlwb, nws zoo tiv thaiv cov neurons los ntawm kev puas tsuaj- yog li tswj thiab txhim kho kev txawj ntse - los ntawm cov txheej txheem xws li tshuaj tiv thaiv - mob, tiv thaiv -apoptotic, thiab cov tshuaj tiv thaiv antioxidant. Nyob rau hauv cov ntsiab lus ntawm cerebral ischemia thiab neurodegenerative mob, salidroside pab txo qis neuronal puas thiab inflammatory teb thaum txhim kho kev nco thiab kev kawm muaj peev xwm. Tsis tas li ntawd, nws txhim kho mitochondrial muaj nuj nqi los muab cov hlwb hlwb nrog lub zog txaus thiab txhawb nqa kev qhia ntawm ntau yam neurotrophic yam, yog li txhawb kev noj qab haus huv thiab kho cov paj hlwb.
Salidroside rau daim tawv nqaij
Salidroside muaj ntau yam kev tiv thaiv thiab kho cov txiaj ntsig zoo rau daim tawv nqaij, feem ntau los ntawm kev ua los ntawm cov txheej txheem xws li tshuaj tiv thaiv oxidation, txhawb nqa collagen synthesis, tiv thaiv kev yees duab, thiab inhibition ntawm melanin ntau lawm. Hais txog kev ncua ntawm daim tawv nqaij laus, salidroside modulates TGF- 1 qhia hauv macrophages thiab txhawb nqa fibroblast proliferation, migration, thiab collagen synthesis; Cov kev ua no nce dermal thickness, txhim kho daim tawv nqaij elasticity, thiab txo wrinkles. Tsis tas li ntawd, nws muaj txiaj ntsig zoo tshem tawm cov pa oxygen reactive (ROS), txhim kho kev ua haujlwm ntawm cutaneous antioxidant enzymes (xws li SOD thiab GSH-Px), inhibits lipid peroxidation, thiab txo oxidative puas tsuaj los ntawm ultraviolet hluav taws xob. Nyob rau hauv cov nqe lus ntawm daim tawv nqaij brightening, salidroside inhibits melanogenesis, yog li pab txhim kho daim tawv nqaij pigmentation.
Dab tsi yog Kev Siv ntawm salidroside hmoov?
SalidrosideNtxiv
Qhov no yog thawj daim ntawv thov cheeb tsam rau Rhodiola extract. Nrog nws cov khoom tseem ceeb los tiv thaiv - qaug zog thiab muaj peev xwm los txhim kho lub cev ua siab ntev rau hypoxia raws li nws cov ntsiab lus muag, nws tau siv dav hauv cov tshuaj tiv thaiv- qaug zog, cov khoom noj khoom haus kis las, thiab cov khoom noj tshwj xeeb rau cov neeg taug kev siab -. Los ntawm kev ua kom tshem tawm cov lactic acid thiab txhawb cov metabolism hauv lub zog, nws pab cov neeg ncaws pob rov qab sai dua tom qab kev kawm hnyav. Nws cov khoom adaptogenic kuj nquag siv nyob rau hauv ntau yam khoom noj khoom haus los pab cov neeg niaj hnub no txo kev ntxhov siab thiab txhim kho sub-kev noj qab haus huv, txhawb nqa lub cev thiab lub hlwb kom zoo- yog los ntawm kev tswj lub cev kev ntxhov siab thiab txhawb nqa tag nrho cov resilience rau txhua hnub ib puag ncig thiab kev nyuaj siab.
Salidroside Pharmaceuticals
Qhov no yog nws qhov siab -tus nqi- ntxiv thaj chaw thov. Kev tshawb fawb tsom mus rau nws cov teebmeem neuroprotective rau kev tsim cov tshuaj muaj peev xwm los txhim kho kev paub, tiv thaiv kev nyuaj siab, thiab tawm tsam Alzheimer's disease. Nws lub peev xwm los tiv thaiv kab mob plawv (xws li tiv thaiv myocardial ischemia thiab txhim kho microcirculation) kuj ua rau nws cov tshuaj tshiab rau kev kho mob ntawm cov kab mob plawv. Tsis tas li ntawd, nws cov antioxidant muaj zog thiab tiv thaiv - cov khoom ua rau mob ua rau muaj kev cuam tshuam rau kev ncua kev laus thiab tiv thaiv cov kab mob sib kis.
Salidroside Tshuaj pleev ib ce
Salidroside yog cov khoom muaj npe nrov hauv cov khoom siv tawv nqaij siab - kawg. Nws lub peev xwm antioxidant muaj zog tuaj yeem tiv thaiv cov dawb radicals uas ua rau tawv nqaij laus, ua lub luag haujlwm hauv kev tiv thaiv -wrinkle thiab ncua kev yees duab. Los ntawm kev ua kom Nrf2/ARE antioxidant txoj hauv kev, nws txhim kho cov tawv nqaij tiv thaiv kab mob endogenous, muab kev tiv thaiv ntev ntev rau cov neeg ua phem ib puag ncig xws li UV hluav taws xob thiab cov pa phem. Nyob rau tib lub sijhawm, nws tseem tuaj yeem txhawb cov tawv nqaij metabolism thiab microcirculation, txhim kho cov tawv nqaij tawv tawv, thiab muab cov khoom cuam tshuam ntawm cov tawv nqaij brightening thiab ncua kev laus. Tsis tas li ntawd, nws nkoos collagen synthesis thiab inhibits matrix metalloproteinases (MMPs) kom txo collagen tawg, yog li txhim kho daim tawv nqaij elasticity thiab firmness. Nws yog feem ntau siv rau hauv cov khoom xws li cov tshuaj pleev ib ce thiab lub ntsej muag cream, thiab tau nce ntxiv rau hauv qhov ncauj qhov ntswg thiab qhov muag cream rau cov txiaj ntsig zoo ntawm daim tawv nqaij rejuvenation.
Salidroside Side Effects yog dab tsi?
Salidroside feem ntau suav hais tias muaj kev nyab xeeb thiab zoo -thov thaum noj ntawm cov tshuaj pom zoo. Txawm li cas los xij, zoo li txhua yam bioactive compound, nws yuav ua rau muaj kev phiv rau qee tus neeg, feem ntau thaum noj ntau ntau.Cov kev mob tshwm sim feem ntau yog mob me me thiab cuam tshuam rau nws cov tshuaj stimulant -zoo li cov khoom. Cov no tuaj yeem suav nrog kev ntxhov siab, ntxhov siab, insomnia (tshwj xeeb tshaj yog tias noj lig hnub), thiab mob taub hau me. Vim tias nws muaj peev xwm cuam tshuam rau ntshav siab thiab ntshav qab zib, cov tib neeg uas muaj feem cuam tshuam txog kev kho mob yuav tsum siv ceev faj.
Qhov twg yuav qhov zoo tshaj plaws Salidroside?
Peb tau koom nrog kev lag luam cog qoob loo ntau tshaj kaum xyoo thiab tau tsim peb tus kheej ua cov chaw tsim khoom lag luam txhim khu kev qha thiab cov khoom lag luam siab -cov nroj tsuag zoo hauv Suav teb. Nrog kev paub dhau los hauv cov khoom siv raw khoom, kev rho tawm, purification, thiab kev tswj kom zoo, peb tuav cov txheej txheem nruj thoob plaws tag nrho cov txheej txheem ntau lawm.Rau peb98% Salidroside hmoov, peb ua tib zoo tswj cov ntaub ntawv raw los ntawm qhov pib thiab xaiv qhov tsim nyog botanical los xyuas kom meej qhov sib xws thiab purity. Peb cov txheej txheem ntau lawm tau txais kev txhawb nqa los ntawm cov kws tshaj lij extraction thiab purification technologies, thaum txhua batch undergoes nruj zoo soj ntsuam ua ntej xa zaub mov.Yog hais tias koj xav nyob rau hauv peb Salidroside hmoov, thov koj xav tias dawb rautiv tauj pebntawminfo@kintaibio.com.
FAQ
Q: Qhov txawv ntawm Rosavin thiab salidroside yog dab tsi?
A: Rosavin thiab salidroside yog ob qho tib si cov khoom xyaw tseem ceeb hauv Rhodiola rosea, tab sis lawv muaj cov qauv tshuaj sib txawv. Rosavin belongs rau phenylpropanoid glycoside chav kawm, thaum salidroside belongs rau phenylethanol glycoside chav kawm. Ob leeg muaj kev tiv thaiv- qaug zog thiab cov khoom ua kom muaj zog, tab sis kev tshawb fawb tau pom qhov sib txawv ntawm lawv cov txheej txheem ntawm kev ua thiab muaj zog. Nws yog feem ntau ntseeg tias tus qauv Rhodiola rosea extract yuav tsum muaj ob qho tib si ntawm cov khoom no los tsim cov txiaj ntsig zoo sib xws.
Q: rhodiola ua dab tsi rau koj lub cev?
A: Rhodiola rosea yog cov tshuaj kho kom haum xeeb uas feem ntau ua rau tib neeg cov kab mob neuroendocrine thiab lub zog metabolism. Nws pab lub cev tiv thaiv kev ntxhov siab ntawm lub cev thiab kev puas siab puas ntsws los ntawm kev tswj kev tso tawm cov tshuaj hormones kev ntxhov siab xws li cortisol, yog li txo qis qaug zog thiab txhim kho kev ua siab ntev thiab kev ntxhov siab. Ib txhij, nws txhawb kev tsim cov cellular zog molecules (xws li ATP), txhim kho kev siv oxygen hauv lub hlwb thiab kev txawj ntse xws li kev nco thiab kev xav. Tsis tas li ntawd, nws muaj qee yam kev tiv thaiv - ntxhov siab vim thiab lub siab xav- txhawb nqa cov teebmeem. Nws cov khoom xyaw tseem ceeb (xws li rhodioloside thiab rosavin) ua haujlwm ua ke los txhawb nqa tag nrho homeostasis thiab yoog raws.
Cim npe nrov: Tuam Tshoj salidroside hmoov manufacturers, lwm tus neeg, Hoobkas
