Macleaya Cordata Extract

Noj qab haus huv^®Macleaya Cordata Extract(MCE) yog muab los ntawm cov pods ntawm Papilionaceae cog Papilion. Cov khoom no siv lub hom phiaj extraction thev naus laus zis los txhawb tag nrho cov alkaloids, feem ntau sanguisorbin thiab celandine, ua tiav cov ntsiab lus ntawm ntau dua 60%. Kev tshawb fawb dav dav thiab daim ntawv thov tau lees paub nws qhov dav -spectrum antibacterial, tiv thaiv- mob, thiab kev loj hlob- txhawb kev lom neeg. Cov txheej txheem ntau lawm ua raws li cov qauv thoob ntiaj teb xws li GMP, HACCP, ua kom ruaj khov thiab tswj tau zoo. Nws tuaj yeem siv dav hauv kev ua liaj ua teb thiab pub khoom noj, pab txhawb kev noj qab haus huv tsiaj txhu. Thov koj txhob xav li castiv tauj pebntawminfo@kintaibio.com.

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Extraction:Macleaya cordata yog muab rho tawm nrog ethanol.

Concentration & Dissolution:Cov extract yog concentrated thiab yaj nyob rau hauv acidified dej.

Kev sib cais:Theem aqueous yog sib cais.

Basification & Precipitation:Theem aqueous yog basified (piv txwv li, nrog NH₄OH) kom precipitate crude alkaloids.

Muab cais nyob ib leeg:Crude alkaloids yog sau los ntawm centrifugation los yog pom.

Purification:Purification ntawm silica gel chromatography.

Dej nag kawg:Sanguinarine- cov feem ntau nplua nuj yog tsim los ua kom cov ntshiab sanguinarine.

Sau:Ntshiab sanguinarine yog lim thiab qhuav.

1.KINTAI Macleaya Cordata Extract COA

2.KINTAI Macleaya Cordata Extract cov ntsiab lus

Sanguinarine siv nws thawj cov teebmeem lom neeg los ntawm ntau lub tswv yim, feem ntau tsom rau cov cellular daim nyias nyias thiab cov kev taw qhia tseem ceeb. Nws lub luag haujlwm tseem ceeb suav nrog kev sib cuam tshuam rau hauv DNA, uas cuam tshuam DNA replication thiab transcription, ua rau cell voj voog ntes thiab apoptosis. Tsis tas li ntawd, sanguinarine muaj zog tiv thaiv kev ua haujlwm ntawm Na + / K+-ATPase twj tso kua mis, ib qho enzyme tseem ceeb rau kev tswj cov cellular membrane muaj peev xwm. Qhov no inhibition cuam tshuam ionic gradients thiab impairs tseem ceeb cellular zog.

Ib qho tseem ceeb niaj hnub mechanism yog qhov inhibition ntawm Nuclear Factor-kappa B (NF-κB) taw qhia txoj hauv kev. Sanguinarine thaiv kev ua kom muaj zog thiab hloov pauv nuclear ntawm NF-κB, tus kws tswj xyuas qhov mob, kev muaj sia nyob ntawm tes, thiab kev loj hlob. Los ntawm kev ua li ntawd, nws inhibits qhov kev qhia ntawm pro-inflammatory cytokines, anti-apoptotic proteins, thiab lwm yam noob caj noob ces tseem ceeb rau kev mob qog noj ntshav. Tsis tas li ntawd, sanguinarine tuaj yeem ua rau muaj kev tsim cov pa oxygen reactive (ROS), ua rau muaj kev ntxhov siab oxidative uas ua rau cov cellular puas ntxiv thiab txhawb nqa apoptotic cell tuag. Qhov no ntau yam - phiajcim mus kom ze, cuam tshuam cov khoom siv caj ces, kev ncaj ncees ntawm daim nyias nyias, thiab qhov tseem ceeb ntawm kev sib txuas lus, txhawb nqa sanguinarine's potent antimicrobial, tiv thaiv- mob, thiab tiv thaiv- cov kab mob qog noj ntshav.

(Reference:https://www.sciencedirect.com/science/article/pii/S0753332224002907)

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Cov tshuaj tiv thaiv -inflammatory thiab Antioxidant nyhuv

Sanguinarine thiab chelerythrine muaj zog tiv thaiv - cov kab mob inflammatory. Lawv ua hauj lwm los ntawm inhibiting qhov ua kom NF-κB txoj kev taw qhia, ib qho tseem ceeb regulator ntawm o, yog li txo cov zus tau tej cov pro-inflammatory cytokines zoo li TNF- thiab IL-6. Raws li qhov tshwm sim, cov alkaloids no ua cov tshuaj antioxidants, tshem tawm cov dawb radicals thiab tiv thaiv cov ntaub so ntswg los ntawm oxidative kev nyuaj siab, uas pab kom rov zoo sai dua los ntawm kev mob thiab kev puas tsuaj.

Daim tawv nqaij noj qab haus huv thiab kev siv tshuaj pleev ib ce

Hauv cov tshuaj pleev ib ce, cov extract cov tshuaj tiv thaiv kab mob thiab tiv thaiv - cov khoom siv inflammatory yog leveraged los kho cov tawv nqaij mob xws li pob txuv, dermatitis, thiab gingivitis. Nws pab txo qhov mob pob txuv los ntawm kev tsom cov kab mob Cutibacterium acnes thiab calming cov kab mob sib kis. Nws siv hauv cov khoom kho qhov ncauj pab tswj cov quav hniav - tsim cov kab mob thiab tswj cov pos hniav.

Kev Txhawb Txoj Kev Noj Qab Haus Huv Hauv Cov Tsiaj

Nyob rau hauv cov tsiaj nyeg thiab nqaij qaib ntau lawm, lub extract yog dav siv raws li ib tug pub additive. Nws txhim kho plab noj qab haus huv los ntawm kev hloov cov hnyuv microbiota, suppressing cov kab mob phem thaum txhawb cov txiaj ntsig. Qhov kev ua no txhim kho kev ncaj ncees ntawm lub plab barrier, txo cov kab mob raws plab, thiab txhim kho kev nqus ntawm cov as-ham. Yog li ntawd, nws txhim kho kev loj hlob kev ua tau zoo thiab tag nrho cov tsiaj noj qab haus huv, ua ib qho kev hloov zoo rau cov tshuaj tua kab mob kev loj hlob.

Tsiaj Pub Additives

Qhov no yog qhov tseem ceeb tshaj plaws thiab dav siv rau Macleaya Cordata Extract. Raws li ib tug natural nroj tsuag extract, nws yog siv los ua lwm txoj rau tshuaj tua kab mob kev loj hlob txhawb nqa. Nws lub luag haujlwm tseem ceeb yog txhawm rau txhim kho cov tsiaj plab noj qab haus huv los ntawm inhibiting cov kab mob phem (xws li Gram- cov kab mob zoo) thiab txhawb kev nqus cov as-ham, yog li txhim kho kev loj hlob, kev hloov pauv hloov pauv, thiab kev noj qab haus huv tag nrho ntawm cov tsiaj nyeg thiab nqaij qaib xws li npua thiab qaib.

Veterinary Field

Hauv kev yug tsiaj, Macleaya Cordata Extract yog siv los tiv thaiv thiab kho cov kab mob hauv plab hnyuv, xws li swine dysentery. Nws muaj zog tiv thaiv kab mob thiab tiv thaiv - cov khoom siv inflammatory pab tswj kev kis kab mob, txo qhov tshwm sim ntawm raws plab, txo nqi kho mob hauv cov txheej txheem yug me nyuam, thiab zam qhov teeb meem ntawm cov tshuaj chemical residues.

Sanguinarine rau lub qhov ncauj

Sanguinarine muaj cov ntawv thov tseem ceeb hauv kev saib xyuas qhov ncauj. Nrog nws qhov dav -spectrum thiab muaj zog tiv thaiv kab mob, nws muaj txiaj ntsig zoo inhibits cov kab mob loj ua rau cov quav hniav thiab gingivitis (xws li Streptococcus). Yog li ntawd, nws tau dav ntxiv rau cov khoom xws li tshuaj txhuam hniav thiab tshuaj ntxuav qhov ncauj, nrog rau nws cov haujlwm tseem ceeb yog los txo cov quav hniav, txo cov gingivitis, thiab txhim kho qhov ncauj tag nrho. Nws cov keeb kwm ntuj kuj ua rau nws yog ib qho kev xaiv zoo tshaj plaws rau cov tshuaj tua kab mob.

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Kev siv tshuaj tua kab mob hauv cov tsiaj nyeg thiab nqaij qaib pub yog tsuas yog siv rau kev tiv thaiv thiab kho cov kab mob thiab txhawb kev loj hlob ntawm cov tsiaj nyeg thiab nqaij qaib, yog li tsav txoj kev loj hlob sai ntawm kev lag luam tsiaj txhu thiab nqaij qaib. Txawm li cas los xij, kev siv tshuaj tua kab mob ntev ntev tau ua rau muaj tshuaj tiv thaiv kab mob ntau ntxiv hauv tsiaj- cov kab mob tau los, thiab cov tshuaj tiv thaiv kab mob cuam tshuam rau tib neeg kev noj qab haus huv los ntawm nqaij cov khoom seem, fecal excretion, thiab lwm txoj hauv kev. Nrog rau qhov muaj hnub nyoog ntawm kev txwv tshuaj tua kab mob hauv cov tsiaj nyeg thiab nqaij qaib pub, kev txhim kho kev nyab xeeb thiab siv tau cov tshuaj tua kab mob yog qhov tseem ceeb tshwj xeeb rau kev txhim kho kev loj hlob thiab kev tsim khoom ntawm cov tsiaj nyeg thiab nqaij qaib.

Macleaya Cordata Extract muaj txiaj ntsig zoo rau kev txhim kho cov leeg nqaij zoo thiab cov hnyuv metabolism ntawm broilers. Nws yog dav siv nyob rau hauv cov tsiaj nyeg thiab nqaij qaib ntau lawm, tab sis tus nqi ntxiv txawv nyob rau hauv ntau hom tsiaj. Cov ntaub ntawv tshawb fawb hauv tsev thiab txawv teb chaws ntawm Borax hauv cov tsiaj nyeg thiab nqaij qaib feem ntau yog tsom rau broilers, tab sis cov ntawv thov cuam tshuam me ntsis nyob ntawm seb hom broiler thiab hnub nyoog. Ntxiv Macleaya Cordata Extract rau kev noj haus tuaj yeem txhim kho kev loj hlob qeeb ntawm broilers los ntawm necrotic enteritis, txhim kho lawv lub cev tsis muaj zog, thiab yog li txhawb kev loj hlob.

(Siv: Cov nyhuv ntawm Macleaya Cordata Extract ntawm kev loj hlob kev ua haujlwm, kev ua haujlwm antioxidant thiab nqaij zoo ntawm broiler qaib)

Puas yog sanguinarine tshuaj lom? Thaum Macleaya Cordata Extract muaj ntau yam kev ua si lom neeg, nws cov kev mob tshwm sim feem ntau tshwm sim los ntawm qhov muaj peev xwm toxicity ntawm nws cov khoom tseem ceeb -benzophenanthridine alkaloids (xws li sanguisorbin thiab chelidonine). Kev siv ntawm cov koob tshuaj pom zoo feem ntau muaj kev nyab xeeb, tab sis kev siv ntau dhau los yog siv ntev yuav ua rau muaj kev cuam tshuam tsis zoo. Hauv kev siv tsiaj, kev siv tshuaj ntau dhau yuav ua rau mob plab hnyuv, xws li tsis qab los noj mov, raws plab, lossis plab hnyuv tsis txaus. Kev kam rau siab yuav qis dua hauv qee hom lossis tsiaj nyob hauv kev ntxhov siab. Muaj kev txhawj xeeb ntxiv yog nws qhov peev xwm genotoxicity thiab cytotoxicity; koob tshuaj ntau yuav ua rau cov kab mob metabolic xws li lub siab. Yog li ntawd, nyob rau hauv kev siv tswv yim, tshwj xeeb tshaj yog nyob rau hauv lub teb ntawm pub additives, nws yog ib qho tseem ceeb kom nruj me ntsis ua raws li cov lus pom zoo noj thiab ua tib zoo saib xyuas cov lus teb rau tsiaj kom ruaj ntseg thiab ruaj ntseg siv.

KINTAI Macleaya Cordata Extract, nrog nws ntau dua 60% sanguinarine cov ntsiab lus, sawv ua qhov zoo tshaj plaws, ua kom muaj zog thiab ua haujlwm zoo ib yam rau peb cov neeg siv khoom. Peb muab cov kev daws teeb meem zoo tshaj plaws, zoo li OEM & ODM kev pabcuam, tailoring lub concentration thiab formulation ntawm peb cov extracts kom tau raws li cov kev cai ntawm ntau yam kev siv, los ntawm cov tsiaj pub additives rau cov khoom tu tawv nqaij. Tsis tas li ntawd, peb cov txheej txheem tsim khoom thiab cov khoom kawg tau txais kev txhawb nqa los ntawm cov ntawv pov thawj thoob ntiaj teb nruj, suav nrog ISO thiab GMP, lav cov qauv siab tshaj plaws ntawm kev ua tau zoo, kev nyab xeeb, thiab kev taug qab. Qhov kev sib xyaw ua ke ntawm kev coj dawb huv zoo tshaj, hloov kho tau yooj yim, thiab kev lees paub thoob ntiaj teb tau lees paub ua rau KINTAI koj tus khub txhim khu kev qha thiab qib siab rau cov kev daws teeb meem ntuj.

Yog tias koj txaus siab rau Kintai'sMacleaya Cordata Extract, thov koj txhob xav li castiv tauj pebntawminfo@kintaibio.com.

Cim npe nrov: Tuam Tshoj macleaya cordata extract manufacturers, lwm tus neeg, Hoobkas