Berberine hydrochloride Chaw tsim tshuaj paus thiab tsum
Siv dav hauv kev kho mob hauv Suav teb, berberine hydrochloride nthuav tawm dav dav ntawm cov khoom siv tshuaj. Cov no suav nrog tshuaj tua kab mob, tiv thaiv- mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob, thiab ntshav- qabzib- txo cov teebmeem.
Berberine hydrochloride, tsim los ntawmNoj qab haus huv®, yog ib qho tseem ceeb bioactive compound tau los ntawm Coptis Chinensis cog (tseem hu ua Suav Goldthread). Chemically cais raws li oxalate alkaloid nrog lub npe systematic * 8,9-dihydro-5-methoxy-2,3-methylenedioxy-6H-benzofuro[3,2-c][1]benzazocin-6-ib hydrochloride *, nws tau ntev tau siv nyob rau hauv cov tshuaj suav tshuaj. Cov tshuaj no tshwj xeeb tshaj yog pom zoo rau nws cov kev ua tau zoo hauv kev kho mob plab zom mov thiab tswj cov ntshav qabzib.Yog tias koj xav tau 97% 98% berberine hydrochloride, thov koj xav tiv tauj peb ntawminfo@kintaibio.com.
KINTAI Berberine hydrochloride COA
KINTAI Berberine hydrochloride Specifications
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Yam khoom |
Kev piav qhia |
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Tshuaj npe |
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride |
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Kev qhia tshwj xeeb |
97% & 98% Berberine hydrochloride |
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CAS Nr |
633-65-8 |
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Molecular Formula |
C₂₀H₁₈ClNO₄ |
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Molecular Luj |
371,81 g / mol |
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Qhov tshwm sim |
Yellow crystalline hmoov |
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Melting Point |
Decomposes ntawm kwv yees li 200 degree |
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Solubility |
Dej: me ntsis soluble |
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Optical Activity |
Optically inactive (Nws yog quaternary ammonium ntsev) |
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Chemical Structure |
Lub ntuj quaternary ammonium ntsev los ntawm pawg protoberberine ntawm benzylisoquinoline alkaloids. |
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Kev ruaj ntseg |
Nyob ruaj khov nyob rau hauv kev pom zoo cia. Incompatible nrog muaj zog oxidizing neeg sawv cev. |
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pKa |
pKa ≈ 2.47 (rau conjugate acid ntawm tertiary amine precursor) |
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UV-Vis Spectroscopy |
λ_max (hauv ethanol): ~ 345 nm thiab ~ 425 nm, pab txhawb nws cov xim daj daj. |
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Chemical & Physical Properties
| CAS Nr | 633-65-8 | Qhov ntom | 1.654 g/cm3 |
| Molecular Formula | C20H18ClNO4 | Molecular Luj | 371.81 |
| Melting Point | 204-206℃(txog.) | Boiling Point | N/A |
| Solubleness | Soluble hauv methanol | Txoj Kev Xeem | HPLC |
Berberine Hydrochloride Dosage
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Qeb |
Daim ntawv thov / Indication |
Hom Dosage Range & Notes |
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Ib txwm siv & siv thawj zaug |
Kab mob Gastroenteritis & Diarrhea |
Cov neeg laus: 300-500 mg, noj 3 zaug ib hnub. Kev kho mob feem ntau yog 3-7 hnub. Nws feem ntau noj yog ua ntej lossis tom qab noj mov. |
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Kev siv niaj hnub & ntxiv |
Ntshav Qab Zib Management (Type 2 Diabetes/Pre-diabetes) |
500 mg, noj 2-3 zaug ib hnub nrog zaub mov (tag nrho 1000-1500 mg / hnub). Qhov tseem ceeb: Qhov no yuav tsum tau ua raws li kev saib xyuas kev kho mob vim tias nws tuaj yeem cuam tshuam nrog cov tshuaj noj ntshav qab zib thiab ua rau cov ntshav qab zib tsawg. |
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Ntshav Lipid Management (High Cholesterol / Triglycerides) |
500 mg, noj 2 zaug ib hnub nrog zaub mov (tag nrho 1000 mg / hnub). Feem ntau siv los ua ib qho ntxiv rau kev noj zaub mov thiab kev hloov kev ua neej. |
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Polycystic Ovary Syndrome (PCOS) |
500 mg, noj 2-3 zaug ib hnub nrog zaub mov (tag nrho 1000-1500 mg / hnub). Siv los txhim kho insulin rhiab heev thiab metabolic tsis. |
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Kev txiav txim siab dav dav |
Daim ntawv |
Feem ntau muaj nyob rau hauv cov ntsiav tshuaj lossis tshuaj ntsiav. |
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Kev tswj hwm |
Noj nrog lossis tsis ntev tom qab noj mov los txhim kho kev ua siab ntev thiab siv nws cov ncej - noj mov glycemic nyhuv. |
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Kev nyab xeeb |
Feem ntau zoo - zam. Cov kev mob tshwm sim muaj xws li cem quav, tsam plab, lossis mob plab. Contraindicated nyob rau hauv cev xeeb tub, lactation, thiab nyob rau hauv cov neeg uas muaj G6PD deficiency (vim muaj kev pheej hmoo ntawm hemolysis). |
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Lus Cim Tseem Ceeb |
Disclaimer: Cov ntaub ntawv no yog rau kev kawm nkaus xwb. Nco ntsoov sab laj tus kws kho mob ua ntej pib cov tshuaj ntxiv lossis tshuaj los txiav txim siab npaum li cas rau koj tus mob tshwj xeeb thiab kom tsis txhob muaj kev cuam tshuam tshuaj. |
Cov txiaj ntsig ntawm Berberine hydrochloride
Antibacterial Action: Multifaceted tiv thaiv tiv thaiv kab mob
Coptis cag extract nthuav tawm qhov muaj zog thiab dav -spectrum antibacterial kev ua haujlwm uas txuas ntxiv tshaj qhov cuam tshuam yooj yim, ua rau nws yog lub hauv paus hauv kev tawm tsam cov kab mob sib kis. Nws lub zog yog tshwj xeeb tshaj yog tawm tsam plab hnyuv kab mob: kab mob plab bacilli (xws li, Shigella spp.) thiab Escherichia coli yog lub hom phiaj tseem ceeb, vim tias cov khoom sib txuas cuam tshuam lawv cov phab ntsa ntawm tes, cuam tshuam nrog DNA replication, thiab inhibits synthesis ntawm cov proteins tseem ceeb, zoo halting lawv proliferation. Qhov kev siv ob npaug no tsis yog tsuas yog tua cov kab mob uas twb muaj lawm tab sis tseem tiv thaiv kev kis kab mob hauv lub plab zom mov.
Anti-Arrhythmic Effects: Modulating Cardiac Function ntawm Cellular Level
Cov tshuaj tiv thaiv -arrhythmic zog ntawm berberine hydrochloride hmoov stems los ntawm nws ncaj qha cuam tshuam nrog cov ntaub so ntswg plawv, qhov uas nws exerts meej tswj cov teebmeem ntawm myocardial electrophysiology. Cov kev tshawb fawb qhia tias nws ua rau cov ion channel hauv plawv, tshwj xeeb tshaj yog los ntawm inhibiting ntau sodium thiab calcium influx thaum tswj cov poov tshuaj efflux- cov txheej txheem tseem ceeb uas tswj lub plawv hluav taws xob. Qhov kev hloov pauv no pab ua kom lub plawv dhia tsis zoo, xws li atrial fibrillation, ventricular premature beats, thiab supraventricular tachycardia, los ntawm kev ncua lub sij hawm refractory ntawm cov leeg mob plawv thiab tiv thaiv kev ua tsis zoo ntawm impulse.
Kev kho mob ntawm plab hnyuv: Targeting cag ua rau mucosal puas
Berberine hydrochloride hmoov txoj kev ua tau zoo hauv cov kab mob plab hnyuv loj tshwm sim los ntawm kev sib xyaw ua ke ntawm cov kua qaub-suppressive, mucosal- tiv thaiv, thiab rov tsim cov teebmeem. Nws ncaj qha inhibits qhov tso tawm ntawm gastric acid los ntawm kev thaiv cov histamine H2 receptors thiab txo cov proton twj tso kua mis, yog li txo cov kua qaub acidity -ib qho tseem ceeb hauv kev tiv thaiv ntxiv yaig ntawm lub plab thiab duodenal mucosa nyob rau hauv tej yam kev mob xws li peptic rwj.
Kev siv Berberine hydrochloride
Berberine Hydrochloride Hauv Pharmaceutical
Coptis cag extract hmoov plays lub luag haujlwm tseem ceeb hauv kev lag luam tshuaj. Nws muaj cov cim inhibitory cuam tshuam rau cov kab mob pathogenic xws li cov kab mob thiab cov kab mob fungi, ua rau nws siv cov tshuaj muaj nyob rau hauv kev kho mob ntawm plab hnyuv kab mob (xws li bacillary dysentery, enteritis). Los ntawm kev cuam tshuam nrog cov txheej txheem metabolic ntawm cov kab mob pathogenic, nws zoo tiv thaiv kev tsim cov kab mob thiab txo cov tsos mob xws li raws plab thiab mob plab. Lub caij no, kev tshawb fawb tsis ntev los no tau pom tias nws tuaj yeem tswj cov piam thaj thiab lipid metabolism, pab txhim kho cov ntshav qab zib hauv cov neeg mob ntshav qab zib hom 2. Nws txhim kho cov tshuaj insulin rhiab heev los ntawm kev ua kom lub AMPK taw qhia txoj hauv kev, dhau los ua ib qho kev xaiv rau kev pab kho mob ntawm cov kab mob metabolic.
Berberine Hydrochloride Hauv Kev Lag Luam Khoom Noj Khoom Haus
Hauv cov khoom lag luam kev noj qab haus huv, Coptis cag extract hmoov yog feem ntau ua rau hauv cov tshuaj ntsiav lossis ntsiav tshuaj thiab siv los ua lub plab hnyuv microecological regulator. Nws tuaj yeem txhawb txoj kev loj hlob ntawm cov kab mob hauv plab uas muaj txiaj ntsig zoo (xws li bifidobacteria), inhibit qhov kev loj hlob ntau ntawm cov kab mob phem, tswj kev sib npaug ntawm cov hnyuv, thiab yog li txhim kho kev zom zaub mov. Tsis tas li ntawd, nws muaj qee yam kev tiv thaiv kab mob - txhim kho cov nyhuv, uas tuaj yeem txhawb kev ua haujlwm ntawm lub cev tiv thaiv kab mob thiab txhim kho lub cev tiv thaiv. Nws yog tshwj xeeb tshaj yog haum rau cov neeg uas tsis muaj zog plab hnyuv ua hauj lwm los yog tsis muaj kev tiv thaiv raws li ib tug noj qab haus huv ntxiv txhua hnub
Berberine Hydrochloride Hauv Tshuaj pleev ib ce
Nrog rau qhov muaj koob meej ntawm cov khoom xyaw ntuj hauv cov tshuaj pleev ib ce, berberine hydrochloride hmoov tau maj mam nyiam vim nws cov tshuaj tiv thaiv - mob thiab antioxidant zog. Hauv cov khoom tu tawv nqaij, nws tuaj yeem inhibit Propionibacterium acnes
Vim li cas thiaj xaiv KINTAI Berberine Hydrochloride?
Hwm Natural Sourcing: Healthkintai®Coptis cag extract hmoov pib nrog kev xaiv zoo ntawm cov ntaub ntawv raw, tshwj xeeb tshaj yog los ntawm cov organic cultivated Coptis chinensis rhizomes nyob rau hauv ecologically pristine cheeb tsam.
Kev tshawb fawb-Cov qauv rov qab:Ntawm lub hauv paus ntawm Healthkintai®Qhov kom zoo dua yog nws kev koom ua ke ntawm kev paub ib txwm muaj nrog niaj hnub scientific nruj. Cov hmoov ua tiav triple- txheej txheem kuaj zoo: ua ntej, kev tshuaj xyuas phytochemical kom paub tseeb alkaloid profile; thib ob, kev ntsuam xyuas microbial load kom ntseeg tau tias tsis muaj menyuam; thiab thib peb, kev ntsuas kev ruaj ntseg nyob rau hauv qhov sib txawv ntawm qhov kub thiab txias.
Kev siv ntau yam:Noj qab haus huv®Coptis cag extract hmoov sawv tawm rau nws cov seamless kev koom ua ke rau hauv ntau pawg khoom, qhia txog lub hom kev nkag siab ntawm ntau yam kev lag luam xav tau. Hauv cov tshuaj, nws ua hauj lwm raws li ib tug active ingredient nyob rau hauv anti- zawv plab thiab tiv thaiv - inflammatory formulations, leveraging nws broad -spectrum antibacterial action.YuavBerberine Hydrochloride, tiv tauj pebntawminfo@kintaibio.com.
FAQ
Q: Dab tsi yog berberine hydrochloride siv rau?
A: Berberine Hydrochloride belongs rau chav kawm ntawm alkaloids lossis tshuaj ntsuab tshuaj. Nws ua lub luag haujlwm tseem ceeb hauv cov ntshav qab zib (glucose) metabolism thiab kev noj qab haus huv ntawm lub plawv.
Q: Puas yog berberine hydrochloride zoo ib yam li berberine?
A: Berberine thiab Berberine hydrochloride (HCL) lossis HCl) tsis zoo ib yam. Berberine yog daj -xim alkaloid pom nyob rau hauv tej yam nroj tsuag raws li tau sau tseg saum toj no. Txawm li cas los xij, Berberine HCL yog berberine crude uas tau hloov kho los ua cov ntsev alkaloidal.
KINTAI Ntawv pov thawj
Cim npe nrov: Tuam Tshoj berberine hydrochloride hmoov manufacturers, lwm tus neeg, Hoobkas
