Galla Chinensis Extract Gallic Acid Hmoov

Galla Chinensis Extract hmoovGallic Acid)yog lub ntuj polyphenolic raw khoom muab tau los ntawm gallnuts thiab tau los ntawm hydrolysis thiab purification txheej txheem. Nws lub ntsiab active tivthaiv yog gallic acid, uas muab cov dej siab dawb -radical scavenging, antioxidant, antimicrobial-anti-inflammatory, hlau-chelating thiab astringent zog. Rau kev siv tshuaj pleev ib ce thiab kev tu tawv nqaij, cov khoom xyaw no nquag siv rau hauv cov tshuaj antioxidant- kho cov qauv los pab tiv thaiv ib puag ncig kev ntxhov siab tshwm sim los ntawm cov dawb radicals thiab soothe tawv nqaij mob. Hauv cov khoom noj khoom haus, nws ua haujlwm raws li cov khoom xyaw ntuj antioxidant feem ntau rau kev tiv thaiv oxidative ntawm cov roj- rog, thiab tseem yog ib qho tseem ceeb hluavtaws nruab nrab rau kev tsim Propyl Gallate (PG). Nyob rau hauv kev lag luam tshuaj- tshuaj lom neeg kev lag luam, nws ua raws li cov tshuaj ua haujlwm nruab nrab uas siv nws cov tshuaj tua kab mob thiab tshuaj astringent. Tsis tas li ntawd, nws tau siv dav hauv cov tshuaj zoo, textile printing -dyeing thiab tanning- kev lag luam.

Cov nroj tsuag-raws li extracts sawv cev rau cov khoom tseem ceeb ntawm Healthkintai^®. Peb khav theeb xyoo ntawm kev ua tau zoo hauv R & D thiab tsim cov botanical rho tawm. Ntawm peb cov khoom,Galla Chinensis Extract Gallic AcidHmoovqeb ua ib qho ntawm peb qhov zoo tshaj plaws - muag cov ntaub ntawv raw. Peb cov ntsiab lus nrov nrov yog 99% hmoov. Sib nrug los ntawm cov qauv kev qhia tshwj xeeb, peb xa cov kev pabcuam customized. Yog tias koj muaj qee qhov kev xav tau rau kev tsim kho qhov project, thov koj xav dawbtiv tauj pebntawmhealth@kintaibio.comthiab qhia koj cov txheej txheem tsim, daim ntawv thov teb thiab kev xav tau. Peb yuav ua cov kev daws teeb meem rau koj lub lag luam.

Kev lag luam thoob ntiaj teb gallic acid tuav ruaj khov- kev loj hlob lub zog, feem ntau yog tsim los ntawm hydrolysis ntawm gallnut tannins thiab segmented rau hauv kws tshuaj -qib, zaub mov- qib thiab kev lag luam- qib specifications. Nws qhov kawg -siv sectors muaj xws li tshuaj intermediates, kev noj haus tshuaj, cosmetic antioxidants, natural food preservatives thiab zoo tshuaj. Asia-Pacific yog lub chaw tsim khoom tseem ceeb nrog Tuam Tshoj ua lub ntiaj teb cov khoom lag luam tseem ceeb xa tawm ntau ntau rau Tebchaws Europe, Amelikas thiab Southeast Asia.

Tsav los ntawm kev huv huv - daim ntawv lo sib txawv, kev thov rau cov khoom xyaw ntuj polyphenol no nce ntxiv, tab sis kev lag luam tau sib tw los ntawm cov khoom nyoos raws caij nyoog - cov khoom hloov pauv ntawm gallnuts uas ua rau cov khoom siv thiab cov nqi tsis hloov. Kev sib tw ua lag luam tsom mus rau kev tswj hwm kev coj dawb huv, eco- cov thev naus laus zis thev naus laus zis thev naus laus zis thiab kev lees paub ua raws thoob ntiaj teb. Pharmaceutical-qib gallic acid muab ntau dua ntxiv- tus nqi, thiab tag nrho kev lag luam yuav txav mus rau kev kho kom zoo dua qub thiab kev tsim qauv nrog rau kev nthuav dav ntawm kev noj zaub mov thiab tus kheej - kev saib xyuas.

Gallic Acid Solubility hauv dej

Puas yog gallic acid soluble hauv dej? Gallic acid yog cais raws li me ntsis soluble rau sparingly soluble hauv dej thiab nws solubility yog kub heev -sensitive. Gallic acid ntawm chav sov (20 degree), solubility ntawm anhydrous gallic acid yog kwv yees li 1.19 g / 100 mL, thaum nws cov monohydrate nthuav tawm me ntsis siab dua solubility ntawm kwv yees li 1.5 g / 100 mL. Nws solubility nce siab nrog qhov kub thiab txias tuaj yeem ncav cuag li 33% hauv cov dej kub npau npau ntawm 100 degree, uas ua rau nws yooj yim soluble hauv dej kub tab sis tsis zoo soluble hauv dej txias.

Gallic Acid Solubility hauv Ethanol

Gallic acid muaj zoo solubility nyob rau hauv ethanol thiab poob rau hauv yooj yim - soluble qeb, nrog nws solubility nce raws li kub nce. Nws lub peev xwm dissolving yog qhov tshwj xeeb tshaj yog nyob rau hauv dej txias. Nyob rau hauv chav tsev kub (kwv yees li 25 degree), 1 g ntawm gallic acid tuaj yeem yaj tag nrho hauv li 6 mL ntawm ethanol. Qhia tawm raws li pawg loj, nws solubility hauv ethanol yog kwv yees li 16%, sib npaug li ntawm 160 g / L.

Gallic Acid Solubility hauv Methanol

Gallic acid yog soluble dawb do hauv methanol, uas qhia qhov solubility siab tshaj plaws ntawm tag nrho cov kuab tshuaj. Ntawm 25 degree, kwv yees li 28.11 g ntawm gallic acid tuaj yeem yaj hauv 100 g ntawm methanol. Thaum qhov kub nce mus txog 50 degree, qhov solubility ntxiv mus rau 30.65 g. Ntawm cov plaub cov kuab tshuaj -methanol, ethanol, dej thiab ethyl acetate, solubility txiav txim ntawm gallic acid yog methanol > ethanol > dej > ethyl acetate, thiab methanol ua cov kuab tshuaj zoo.

Gallic acid yog monomeric phenolic acid, tseem hu ua dawb gallic acid. Diglucosyl gallic acid yog glycoside derivative tsim los ntawm glycosylation hloov kho ntawm gallic acid, nrog ob lub qabzib molecules txuas rau nws cov qauv molecular. Ob qho khoom xyaw sib koom ua ke tib lub gallic-acid niam txiv nucleus thiab ua kom pom kev tshawb fawb- rov qab muaj peev xwm rau cov teebmeem antioxidant, dawb-radical neutralization thiab kev hloov pauv ntawm tyrosinase kev ua haujlwm.

Lawv qhov sib txawv tseem ceeb yog nyob rau hauv dej- cov khoom solubility, tus cwj pwm nkag mus rau ntawm daim tawv nqaij, khaus profile thiab hom kev ua. Gallic acid nta cov lipophilicity siab dua thiab tseem ceeb ntawm kev ua haujlwm lom neeg tseem ua rau muaj kev pheej hmoo siab ntawm daim tawv nqaij khaus. Tom qab hloov kho glycosylation, diglucosyl gallic acid tau txais cov dej zoo heev - solubility thiab txo cov cellular irritation tam sim ntawd. Nws ua rau ntawm daim tawv nqaij los ntawm kev txhawb nqa -tso tawm mechanism kom xa cov tawv nqaij mos-brightening conditioning effect, ua rau nws tau dav heev - siv cov khoom muaj txiaj ntsig hloov pauv hauv cov tshuaj tu tawv nqaij.

Gallic Acid Antimicrobial Activity

Gallic acid yog ib tug natural polyphenolic compound dav pom nyob rau hauv ntau cov nroj tsuag thiab nthuav dav -spectrum bactericidal thiab fungicidal zog tiv thaiv ntau yam kab mob thiab fungi. Nyob rau hauv cov nqe lus ntawm ncaj qha bactericidal teebmeem, gallic acid puas tus qauv ntawm cov kab mob ntawm cov phab ntsa ntawm tes thiab cell membranes thiab ua rau kom cov membrane permeability. Qhov no ua rau cov dej xau ntawm cov khoom tseem ceeb hauv lub cev nrog rau cov nucleic acids thiab cov proteins, thiab thaum kawg ua rau cov kab mob ntawm tes lysis. Nrog rau cov kab mob biofilms, gallic acid tuaj yeem inhibit biofilm tsim nrog rau degrade pre- tsim cov biofilms paub tab. Nws lub hauv paus txheej txheem feem ntau yog los ntawm kev nqis tes ua - kev tswj hwm ntawm sarA, icaA thiab icaD noob qhia, uas txo qis kev tsim tawm ntawm intercellular polysaccharide adhesin thiab ua rau cov kab mob adhesion thiab colonization muaj peev xwm. Tsis tas li ntawd, gallic acid inhibits cov kab mob efflux twj tso kua mis, pab cov tshuaj tua kab mob ua kom muaj txiaj ntsig zoo dua hauv cov kab mob. Thaum ua ke nrog cephalosporins thiab tetracyclines, nws muab cov tshuaj tiv thaiv kab mob muaj txiaj ntsig zoo.

Gallic Acid Antioxidant

Lub peev xwm antioxidant ntawm gallic acid feem ntau yog los ntawm peb pawg phenolic hydroxyl ntawm nws lub nplhaib benzene, ntawm cov vicinal tri-hydroxyl qauv ua lub luag haujlwm tseem ceeb tshaj plaws. Cov qauv no pub dawb hydrogen atoms lossis electrons rau hydroxyl radicals, peroxyl radicals thiab DPPH radicals, thiab hloov nws tus kheej mus rau hauv cov phenoxyl radicals ruaj khov. Nrog cov nyhuv resonance ntawm lub nplhaib benzene thiab intramolecular hydrogen bonds tsim los ntawm cov pawg hydroxyl uas nyob ib sab, kev ruaj ntseg ntawm radical intermediates yog ntxiv txhim kho, yog li tshem tawm cov dawb -radical saw oxidation txheej txheem. Tsis tas li ntawd, gallic acid muaj peev xwm ntawm kev hloov pauv ntawm chelating-hlau ions xws li ferrous ions thiab cuprous ions, txo cov kev ua ntawm Fenton cov tshuaj tiv thaiv thiab inhibiting hlau-kho lipid peroxidation. Nws kuj ua haujlwm los tsim cov tshuaj tua kab mob endogenous nrog rau vitamin C thiab vitamin E.

Gallic acid ua xua

Muaj cov kev tshawb fawb qhia tias gallic acid muaj peev xwm tiv thaiv - allergic soothing los ntawm ob txoj hauv kev:

Inhibition of allergic-inflammatory release: nws modulates cellular signals to reduce mast-cell activation and histamine release, and suppresses the production of inflammatory factor. Nws cov nyhuv cuam tshuam yog piv rau cromolyn sodium.

Kev ntsuas lub cev tiv thaiv kab mob: kev sim tsiaj tau lees paub tias gallic acid modulates T-cov lus teb ntawm tes tiv thaiv kab mob, tshem tawm cov kab mob hauv lub cev thiab cov kab mob hauv cellular infiltration los ntawm kev ua xua rau lub ntsej muag, thiab txo cov kev ua xua - cov cim cim. Nws kuj tseem qhia tau tias muaj peev xwm txo tau cov tawv nqaij o uas cuam tshuam nrog atopic dermatitis.

Gallic Acid rau daim tawv nqaij

Gallic acid rau daim tawv nqaij dawb

Gallic acid yog ib qho zoo heev antioxidant. Nws pab inhibit tyrosinase kev ua haujlwm thiab thaiv cov txheej txheem biochemical tseem ceeb rau kev tsim melanin. Nws alleviates UV-induced oxidative kev nyuaj siab puas tsuaj thiab txhim kho dull, yellowish ntawm daim tawv nqaij laus los ntawm photodamage rau gradual txhim kho ntawm tag nrho cov tawv nqaij translucency. Thov nco ntsoov tias cov khoom xyaw no ua rau cov tawv nqaij - cov teebmeem toning es tsis yog cov tshuaj pleev xim rau ntawm daim tawv nqaij, thiab kev txhim kho yuav tsum tau siv zoo ib yam.

Gallic acid rau pob txuv

Nrog nws cov tshuaj antioxidant thiab tshuaj tua kab mob ntuj, gallic acid txwv tsis pub dhau - kev loj hlob ntawm pob txuv - ua rau cov kab mob thiab cov nyuj hauv zos cov tawv nqaij inflammatory teb. Rau hom oily ntawm daim tawv nqaij, nws eases redness thiab tsis xis nyob tshwm sim los ntawm oxidized sebum thiab pab nyob rau hauv mitigating pom cov tsos mob ntawm inflammatory blemishes. Raws li cov khoom siv tshuaj pleev ib ce, nws tsis yog kev hloov tshuaj. Cov pob txuv hnyav yuav tsum tau kho los ntawm tus kws kho mob dermatologist.

Gallic acid rau cov pob qij txha

Kev raug UV ntev ntev ua rau muaj kev ywj pheej ntau dhau -radical tiam, ua kom cov pigment deposition thiab tsim cov xim pigmented. Los ntawm kev ua haujlwm antioxidant, gallic acid txo qis tsis tu ncua - radical stimulation rau melanocytes, slows ntxiv qhov chaw darkening thiab inhibits pigment thauj mus rau stratum corneum. Cov khoom xyaw no tsuas yog tiv thaiv qhov tshwm sim ntawm qhov tshwm sim thiab ua kom lub ntsej muag pigmentation. Sib sib zog nqus- qhov chaw tawv tawv tsis tuaj yeem tshem tawm tag nrho los ntawm kev kho tawv nqaij ib leeg thiab xav tau ntev- cov txheej txheem tu tawv nqaij.

Gallic Acid rau cov plaub hau

Gallic acid yog lub ntuj polyphenol- cov khoom xyaw nquag. Nws pab inhibit 5 -reductase thiab txo DHT qib. Nws soothes tawv taub hau mob tshwm sim los ntawm NF-κB txoj hauv kev ua kom thiab txo cov tawv taub hau tsis xis nyob los ntawm oxidative kev nyuaj siab. Nws txhim kho redness, khaus thiab ntau ntau sebum secretion ntawm tawv taub hau, thiab eases siab ntawm cov hauv paus plaub hau nyob rau hauv seborrheic tej yam kev mob. Lub caij no, cov khoom xyaw no tshem tawm cov dawb radicals, boosts tawv taub hau lub antioxidant tiv thaiv kab mob, tswj kev noj qab haus huv follicular micro- ib puag ncig thiab txo kev puas tsuaj rau cov hauv paus plaub hau los ntawm lwm yam oxidation.

Gallic Acid rau poob phaus

Gallic acid yog cov nroj tsuag - muab los ntawm ntuj polyphenol. Nws tuaj yeem pab cuam tshuam qhov kev loj hlob thiab kev sib txawv ntawm adipocytes, hloov kho lub cev lipogenic teeb liab txoj hauv kev thiab txo qis lipid ntau dhau. Lub caij no, nws pab tswj cov kev ntxhov siab oxidative thiab txo qis qis - qib o los txhim kho tag nrho cov txheej txheem metabolic thiab muab cov txiaj ntsig txhawb nqa rau kev tswj qhov hnyav. Thov nco ntsoov tias cov khoom xyaw no ua rau tsis muaj roj ncaj qha - hlawv lossis hnyav sai - poob. Nws tsuas yog ua haujlwm pabcuam hauv metabolic los ntawm kev pom kev noj haus. Kev noj qab haus huv qhov hnyav yuav tsum muaj kev tswj hwm calorie kom zoo thiab kev ua lub cev tsis tu ncua thiab tsis tuaj yeem hloov cov khoom noj kom zoo thiab kev noj qab haus huv.

Ellagic acid thiab gallic acid yog ob qho tib si nroj tsuag -polyphenol active tshuaj muab tau los ntawm hydrolyzable tannin tsev neeg. Nyob rau hauv tej yam ntuj tso botanical raw- cov ntaub ntawv systems, lawv sib ze biochemical kev sib raug zoo: gallic acid ua hauj lwm raws li lub hauv paus monomer molecule, thaum ellagic acid yog tsim los ntawm oxidative coupling thiab nplhaib - kaw cov tshuaj tiv thaiv ntawm ob gallic- kua qaub molecules.

Raws li ib qho kev tivthaiv uas muaj qhov hnyav dua molecular, gallic acid muab cov tawv nqaij zoo - nkag tau. Nws lub luag haujlwm tseem ceeb suav nrog kev tshem tawm cov dawb radicals ntau dhau, inhibition ntawm tyrosinase catalytic cov tshuaj tiv thaiv, thiab txo cov oxidation - ua rau cov tawv nqaij mob los ntawm kev hloov kho ntawm NF-κB txoj kev taw qhia, nrog rau kev tsom mus rau kev ua haujlwm antioxidant sai thiab kho kom zoo. Nrog rau qhov sib piv siab dua molecular hnyav, ellagic acid qhia tau tias muaj tshuaj lom neeg zoo dua qub tab sis txwv tsis pub transdermal permeability. Nws tsis feem ntau tsom melanin synthesis; Nws cov txiaj ntsig tseem ceeb yog nyob rau hauv suppressing melanin-txoj kev thauj mus los thiab cuam tshuam kev tsiv teb tsaws thiab kis ntawm melanin paub tab mus rau epidermal keratinocytes.

Ntuj cog extracts xws li pomegranate tev thiab rosemary nquag muaj ob qho tib si active. Thaum ua ke, lawv tsim kom muaj kev sib koom ua ke ntawm daim tawv nqaij -brightening system: gallic acid ua haujlwm ntawm lub hauv paus los cuam tshuam nrog melanin ntau lawm, whereas ellagic acid blocks sab nraud pigment translocation. Qhov kev sib xyaw ua ke no cuam tshuam cov kev txwv tsis pub muaj ntawm txhua qhov muaj thiab muab ntau yam txiaj ntsig ntawm daim tawv nqaij npog los tiv thaiv -oxidation, tiv thaiv- mob thiab xim xim.

Kev siv Gallic Acid

Gallic acid muaj cov tshuaj tua kab mob ruaj khov, tiv thaiv kab mob, tiv thaiv- inflammatory thiab mob astringent zog, ua ib qho tseem ceeb hluavtaws nruab nrab thiab cov qauv siv cov ntaub ntawv nyob rau hauv lub ntiaj teb no kev lag luam kws tshuaj thiab tshuaj. Hauv kev lag luam kws tshuaj, nws tsis tshua muaj kev ncaj qha rau hauv cov tshuaj tiav hauv qhov ncauj thiab feem ntau yog siv los ua cov khoom siv tseem ceeb rau kev sib txuas ntau yam gallate derivatives, uas tau siv dav hauv kev tsim cov khoom siv tshuaj.

Kev siv Gallic Acid Cosmetic

Muab los ntawm cov nroj tsuag ntuj, gallic acid yog dav teev raws li cov khoom tsim nyog tshuaj pleev ib ce thoob ntiaj teb thiab ua haujlwm raws li cov khoom siv nquag siv hauv cov khoom tu tawv nqaij. Nyob rau hauv cov khoom formulations, nws ua tsis tau tsuas yog raws li ib tug zoo tu tawv nqaij active tshuaj, tab sis kuj raws li ib tug formulation stabilizer uas slows down lub oxidative deterioration ntawm roj thiab active Cheebtsam, yog li ncua lub txee lub neej ntawm cov tshuaj pleev ib ce. Hauv kev lag luam kev lag luam, nws cov koob tshuaj yuav tsum nruj me ntsis tswj kom tsis txhob muaj qhov khaus ntawm daim tawv nqaij los ntawm nws cov acidity, kom ua raws li cov kev cai ntawm cov khoom siv tshuaj pleev ib ce hauv ntau lub teb chaws.

Noj qab haus huv^®yog ib lub tuam txhab tshwj xeeb tsom rau R & D, ntau lawm thiab muab cov khoom siv tshuaj pleev ib ce. Nrog xyoo- kev txawj ntse ntev hauv cov nroj tsuag extraction, peb xa cov khoom muaj kev nyab xeeb, ruaj khov thiab siab -purity cov khoom xyaw tseem ceeb nrog rau ib qho -tso tseg cov kev pabcuam rau kev kho kom zoo nkauj thoob ntiaj teb thiab tus kheej- hom kev saib xyuas. Peb qhov zoo tshaj plaws - muag khoom yog99% Suav gallnuts gallic acid hmoov hmoov. Featuring siab purity, zoo heev batch-rau-batch sib xws thiab zoo bioavailability, nws yog dav siv nyob rau hauv kev ua hauj lwm ntawm daim tawv nqaij formulations rau whitening, antioxidant, astringent thiab soothing lub hom phiaj thiab zoo- lees paub los ntawm cov neeg siv khoom thoob ntiaj teb.

Peb kuj muab cov monohydrate gallic acid thiab cov ntaub ntawv ntawm cov khoom siv derivative nrog rau digalloyl qabzib thiab propyl gallate los ua kom muaj kev sib txawv ntawm cov txheej txheem tsim thiab kev siv cov xwm txheej thiab txhawb cov neeg siv khoom los tsim cov khoom lag luam hloov pauv. Ua raws li GMP kev tsim khoom tshwj xeeb, peb siv tag nrho - txheej txheem tswj xws li los ntawm cov khoom siv raw, kev tsim tawm kom tiav - cov khoom ntim. Cov kab mob microorganisms thiab hnyav- qib hlau ua raws li cov qauv kev lag luam kom lav kev nyab xeeb thiab zoo sib xws ntawm txhua pawg.

Muaj ntawv pov thawj nrog cov ntaub ntawv ua tiav, peb tuaj yeem muab tag nrho cov ntaub ntawv txhawb nqa uas xav tau rau kev sau npe tshuaj pleev ib ce thiab ntshuam -export kev lis kev cai clearance los ua kom koj qhov kev yuav khoom thiab kev koom tes ua lag luam. Ua raws li lub hauv paus ntsiab lus ntawm kev ua tau zoo- taw qhia thiab kev pabcuam- tau tsav, peb zoo siab tos txais cov neeg koom tes thoob ntiaj teb rau kev sib tham txog kev lag luam. Xav tias dawb rautiv tauj pebntawmhealth@kintaibio.comrau cov qauv, cov ntaub ntawv technical datasheets thiab cov ncauj lus kom ntxaws. Peb tos ntsoov yuav tsim kev sib nrig sib pab nrog koj.

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