Betulin Powder Chaw tsim tshuaj paus thiab tsum
Betulin hmoovyog ib qho triterpenoid compound muab rho tawm los ntawm birch bark, uas muaj me me los tiv thaiv- mob qog noj ntshav, bactericidal, antiviral, anti-ultraviolet, anti- inflammatory, ceev qhov txhab zoo, tiv thaiv - allergy, anti- laus thiab lwm yam teebmeem, thiab kuj yuav txhim kho cov luster ntawm cov plaub hau puas thiab txhawb cov plaub hau kev loj hlob. Nws yog dav siv nyob rau hauv cov khoom noj, tshuaj, tshuaj lom neeg kev lag luam txhua hnub thiab lwm yam kev lag luam, thiab yog ib yam khoom muaj txiaj ntsig zoo heev. Nws tuaj yeem tau txais los ntawm kev nplua nuj cog qoob loo.
Xi'anNoj qab haus huv® yog lub chaw tsim khoom ntawm betulin, muab siab -zoo, siab -tus qauv betulin. Betulin nthuav tawm cov tshuaj tiv thaiv tseem ceeb - mob, tshuaj tua kab mob, thiab tshuaj tua kab mob, tiv thaiv qog noj ntshav cell proliferation thiab inducing apoptosis, ua rau nws yog ib feem tseem ceeb ntawm kev txhim kho tshuaj tiv thaiv kab mob. Tsis tas li ntawd, cov khoom xyaw no yog siv rau hauv cov khoom tu tawv nqaij kom soothing, kho qhov teeb meem, thiab tiv thaiv kev laus -. Yog hais tias koj xav yuav premium betulin, thovtiv tauj pebntawminfo@kintaibio.com.
Kintai Betulin hmoov zoo
Guaranteed High efficiency:Peb ua tib zoo xaiv, siab -purity betulin raw khoom boasts kev ua si deb tshaj li cov qauv kev lag luam thiab authoritatively validated superior bioavailability, kom ntseeg tau tias tseem ceeb thiab ruaj khov cov txiaj ntsig xws li tiv thaiv - mob, antioxidant, thiab kho.
High-Txoj Kev Tswjhwm Zoo:Peb nruj me ntsis ua raws li thoob ntiaj teb Kev Tsim Khoom Zoo Zoo rau Cov Tshuaj, siv kev tswj xyuas zoo los ntawm cov khoom siv raw traceability kom tiav cov khoom xa tuaj. Peb nruj me ntsis ntsuam xyuas purity, kev ua, thiab kev nyab xeeb ntsuas kom zoo ib yam, txhim khu kev qha zoo.
Customized Services:Peb muab cov khoom customized nrog txawv purity, ntau npaum li cas cov ntaub ntawv, thiab cov kev xaiv dissolution raws li tej daim ntawv thov scenarios thiab formulation yuav tsum tau. Peb kuj muab kev txhawb nqa kev tshaj lij los pab koj tsim cov khoom sib txawv kawg.
KINTAI Betulin Powder Specification & Cov Qauv Zoo
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Khoom npe |
BetulinPowder |
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Extract qhov chaw |
Birch nplooj |
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Specification |
80% 98% Betulin |
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Extraction Solvent |
Ethyl cawv |
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Qhov tshwm sim |
Dawb crystalline hmoov |
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Solubility |
Solubility: soluble hauv ethanol, chloroform, benzene, me ntsis soluble hauv dej txias, roj av ether, thiab lwm yam. |
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Kev txheeb xyuas |
TLC, HPLC |
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Sulfated tshauv |
0.5% NMT |
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Cov hlau hnyav |
NMT 20 ppm |
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Poob Thaum Qhuav |
5.0% NMT |
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Hmoov loj |
80 Mesh, NLT 90% |
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Kev ntsuam xyuas ntawm Betulin Birch Bark (HPLC xeem, feem pua, Tus Qauv hauv Tsev) |
Tsawg kawg . 95.0% |
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Residual Solvents |
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- N- hexane |
NMT 290 PPM |
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- Methanol |
NMT 3000 PPM |
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- Acetone |
NMT 5000 PPM |
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- Ethyl Acetate |
NMT 5000 PPM |
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- Ethanol |
NMT 5000 PPM |
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Tshuaj tua kab |
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- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT thiab p,p' -DDT) |
NMT 0.05 ppm |
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- Aldrin, Endrin, Dieldrin |
NMT 0.01 ppm |
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Microbiological Quality (tag nrho cov suav aerobic) |
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- Cov kab mob, CFU/g, tsis ntau tshaj |
SIB 103 |
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- Pwm thiab poov xab, CFU/g, tsis ntau tshaj |
SIB 102 |
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- E.coli, Salmonella, S. aureus, CFU/g |
Tsis muaj |
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Cia |
Nyob rau hauv ib qho Tight, Light-resistant, thiab qhuav qhov chaw. Tsis txhob Direct Sunshine. |
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Txee lub neej |
24 hli |
Chemical & Physical Properties
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CAS |
No.: 473-98-3 |
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Qhov ntom |
1.0 ± 0.1g / cm3 |
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Melting Point |
256-257℃(lit.) |
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Molecular Formula |
C30H50O2 |
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Molecular Luj |
442.717 |
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Flash Point |
210.9 ± 17.2 degree |
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Exact Mass |
442.381073 |
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PSA |
40.46000 |
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LogP |
9.01 |
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Vapor Siab |
0.0 ± 3.1 mmHg ntawm 25 degree |
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Index ntawm Refraction |
1.525 |
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Kev cia khoom |
2-8 degree |
Dosage ntawm Betulin
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Daim Ntawv Thov / Kawm Hom |
Hom Tshuaj Ntau Yam |
Lus Cim & Ntsiab Lus |
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Hauv Vitro (Cell Culture) Kev Kawm |
1 - 100 μM (ntau ntau) |
Kev noj ntau npaum li cas nyob ntawm seb hom cell, lub sijhawm kho, thiab cov nyhuv xav tau (xws li, tiv thaiv- mob qog noj ntshav, tiv thaiv- mob). Feem ntau sim nrog nws cov derivative, Betulinic Acid. |
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Tsiaj Studies (Mice/rats) |
10 - 200 mg/kg ntawm lub cev hnyav |
Kev tswj qhov ncauj, intraperitoneally, lossis los ntawm kev txhaj tshuaj. Cov koob tshuaj ntau dua (piv txwv li, 50-200 mg/kg) feem ntau siv hauv kev tshawb fawb los tiv thaiv qog. Qhia cov tshuaj toxicity tsawg hauv ntau cov qauv. |
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Tib neeg noj zaub mov ntxiv(Tsis standardized) |
100 - 500 mg ib hnub twg |
Qhov no yog ib tug ntau yam muaj nyob rau hauv kev lag luam muaj tshuaj ntxiv. Nws yog ib qho tseem ceeb kom ua raws li cov neeg tsim khoom cov lus qhia thiab pib ntawm qhov qis kawg ntawm qhov ntau. |
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Extract qhov chaw & Cov txheej txheem tsim khoom
Extract Source
Kintai lub siab - zoo betulin yog qhov zoo tshaj plaws los ntawm qhov pib. Peb xaiv high-zoo birch ntoo los ntawm qhov siab- thaj chaw siab ntawm Northeast Tuam Tshoj, ua kom cov qauv siab thiab zoo rau peb cov ntaub ntawv raw. Los ntawm cov txheej txheem tshwj xeeb rho tawm, peb ua kom siab -purity betulin.
KINTAI Betulin Powder Production process
Raw Material Pretreatment thiab Extraction:Birch bark yog qhuav thiab pulverized. Betulin yog yaj thiab sib cais los ntawm cov khoom siv raw siv cov kuab tshuaj organic los ntawm reflux lossis Soxhlet extraction kom tau txais cov khoom siv raw.
Concentration thiab Preliminary Purification:Cov kuab tshuaj extract tau zoo zoo los ntawm lub tshuab nqus tsev distillation thiab cov kuab tshuaj yog concentrated kom tau txais cov tshuaj tsw qab tsaus nti. Ua ntej purification yog ua los ntawm nag lossis daus kom tshem tawm impurities.
Deep Purification thiab Refining:Kem chromatography yog siv rau kev sib cais tseem ceeb, siv qhov sib txawv ntawm qhov hnyav polarity los xaiv elute thiab sau cov feem ntau nplua nuj hauv betulin. Thaum kawg, recrystallization yog ua kom tau txais cov khoom siv dawb huv heev.
Betulin hauv Anti-inflammatory
Betulin, ib tug natural compound muab rho tawm los ntawm birch bark, boasts zoo xws li muaj ntau thiab tsawg toxicity. Vim nws muaj ntau yam kev ua ub no, suav nrog kev tiv thaiv - mob qog noj ntshav, kev kho mob ntawm daim siab cawv, tshuaj tiv thaiv - mob, thiab tiv thaiv - qaug zog, nws tau dhau los ua lub ntsiab lus kub hauv Kev Tshawb Fawb Tshuaj Hauv Suav Teb. Hauv kev tsim tshuaj, betulin ntau yam tshuaj ua haujlwm zam zam qhov tsis zoo ntawm ib lub tswv yim ntawm kev ua haujlwm thiab kev cuam tshuam rau cov tshuaj tiv thaiv.Bet tuaj yeem cuam tshuam LPS-induced inflammatory teb xws li ROS ntau lawm hauv microglial mitochondria, Nlrp3 inflammasome activation, thiab IL-1 secretion, thiab muaj cov nyhuv ntawm kev tiv thaiv mitochondria.
(siv: Inhibitory effect of betulin on LPS-induced o ntawm microglia, Third Affiliated Hospital of Qiqihar Medical University)
Cov txiaj ntsig ntawm Betulin
Anti-mob qog thiab Anticancer Activity
Qhov no yog thaj chaw uas betulin tau kawm ntau thiab siv zog. Nws nthuav tawm cov kev xaiv inhibitory thiab cytotoxic cuam tshuam tawm tsam ntau cov kab mob qog noj ntshav, thaum pom cov tshuaj toxicity tsawg rau cov hlwb ib txwm muaj.
Antiviral Activity
Btulin thiab nws cov derivatives (tshwj xeeb tshaj yog betulic acid) muaj inhibitory cuam tshuam rau ntau yam kab mob (HIV, HSV, thiab HCV).
Kev tiv thaiv -inflammatory thiab Immunomodulatory Effects
Btulin tuaj yeem tiv thaiv kev tsim cov tshuaj tiv thaiv kab mob, yog li txo cov lus teb inflammatory.
Muaj peev xwm siv tau: Nws muaj peev xwm kho tau cov kab mob xws li mob caj dab, dermatitis, enteritis, thiab atherosclerosis.
Cov teebmeem Antioxidant
Btulin tuaj yeem tshem tawm cov dawb radicals ncaj qha, xws li superoxide anions thiab hydroxyl radicals, thiab txhim khu kev ua haujlwm ntawm cov enzymes antioxidant hauv lub cev, yog li tiv thaiv cov hlwb los ntawm kev puas tsuaj oxidative. Qhov no muaj feem xyuam nrog nws cov tshuaj tiv thaiv - laus, neuroprotective, thiab kev tiv thaiv kab mob plawv.
Kev tiv thaiv kab mob plawv
Lipid-Kev txo qis thiab tiv thaiv- Cov teebmeem atherosclerosis: Kev tshawb fawb tau pom tias betulin tuaj yeem txo qis tag nrho cov roj (TC), triglyceride (TG), thiab qis- ntom lipoprotein (LDL) hauv cov ntshav. Nws slows qhov tsim ntawm atherosclerotic plaques los ntawm regulating lipid metabolism thiab inhibiting intravascular o.
Tiv thaiv tawv nqaij thiab kho
Kev Kho Hniav: Birch bark extract tau ib txwm siv los kho qhov txhab. Betulin tuaj yeem txhawb kev loj hlob thiab kev tsiv teb tsaws ntawm keratinocytes thiab fibroblasts, ua kom cov txheej txheem kho qhov txhab.
Kev siv Betulin
Betulin hauv Pharmaceutical
Betulinyog lub hnub qub molecule hauv kev txhim kho tshuaj tiv thaiv kab mob. Nws lub ntsiab kom zoo dua yog nyob rau hauv nws "xaiv cytotoxicity," zoo inducing apoptosis nyob rau hauv cov qog nqaij hlav cancer thaum txo kev puas tsuaj rau lub cev ib txwm. Nws tau pom tias muaj peev xwm tseem ceeb hauv kev tshawb fawb preclinical rau melanoma thiab leukemia. Tsis tas li ntawd, nws cov tshuaj tiv thaiv -HIV thiab kab mob khaub thuas ua haujlwm, nrog rau nws lub siab- tiv thaiv thiab lipid- txo qis, ua rau nws ua tus neeg sib tw rau ntau yam tshuaj kho. Tam sim no, qhov kev sib tw tseem ceeb nyob hauv kev hloov kho nws cov qauv los daws nws cov dej tsis zoo solubility thiab bioavailability.
Betulin Hauv Tshuaj pleev ib ce thiab kho tus kheej
Qhov no yog betulin qhov loj tshaj plaws daim ntawv thov cheeb tsam. Nrog nws cov tshuaj tiv thaiv antioxidant zoo heev thiab tiv thaiv - cov khoom ua kom mob, nws tau siv dav hauv cov qib siab - kawg cov tshuaj pleev, tshuaj pleev, thiabtu tawv nqaijcov khoom siv los tiv thaiv- kev laus, soothing rhiab tawv nqaij, thiab kho cov tawv nqaij barrier. Nws lub hauv paus chiv keeb zoo sib xws nrog "kev zoo nkauj huv si". Nws kuj tseem tuaj yeem ua ib qho me me, ntuj preservative, txo kev siv tshuaj ntxiv thiab ua kom tau raws li cov neeg siv khoom xav tau kom muaj kev nyab xeeb thiab zoo.
Betulin In Industrial Materials
Raws li thaj chaw tshiab, Betulin Powder yog siv los ua cov khoom siv ntsuab rau kev sib txuas ntawm bio-cov ntaub ntawv raws li. Chemists tau siv nws cov qauv nruj thiab cov khoom siv hydrophobic los hloov nws mus rau hauv polymer monomers rau kev tsim cov biodegradable plastics, resins, thiab super- hydrophobic txheej. Cov txheej txheem no tuaj yeem siv rau textiles, tawv, thiab cov khoom siv hauv tsev, muab cov kev tiv thaiv ib puag ncig thiab cov tshuaj tiv thaiv kev tiv thaiv thaum txo kev cia siab ntawm petrochemicals.
Vim li cas thiaj xaiv KINTAI Betulin Powder?
High Quality:Peb siv cov txheej txheem purification siab heev los xyuas kom meej cov khoom siab purity, tsawg impurity theem, thiab batch robust - mus rau - batch stability, muab kev txhawb txhim khu kev qha rau koj R&D thiab ntau lawm.
Ntau yam:Peb lub siab -purity betulin yog ib qho khoom siv zoo tshaj plaws rau kev siv tshuaj R&D (tiv thaiv- mob qog noj ntshav, tshuaj tiv thaiv kab mob), siab- cov tshuaj pleev ib ce kawg (tiv thaiv- mob, tshuaj tua kab mob), thiab cov zaub mov ua haujlwm. Nws muaj ntau yam kev thov thiab tuaj yeem ua tau raws li koj tus ntoo khaub lig-kev qhuab qhia kev xav tau.
Customizable:Peb muab cov khoom lag luam customized, suav nrog kev sib txawv purity, hmoov particle loj, thiab hnyav solubility, haum rau koj daim ntawv thov tshwj xeeb, kom yoog raws li koj qhov project xav tau.Tiv tauj pebntawminfo@kintaibio.com.
FAQ
Q: Nws puas tsim nyog rau kev siv?
A: Tseeb, nws yog kiag li zoo rau kev siv thaum siv raws li kev sib koom tes.
Q: Dab tsi yog lub sijhawm rau kev siv tiag tiag ntawm nws?
A: Lub sijhawm siv tau tiag tiag ntawm birch bark extract yog 2 xyoos thaum muab tso rau hauv qhov chaw txias thiab qhuav.
Q: Nws puas tuaj yeem siv rau hauv cov khoom tu tawv nqaij?
A: Tseeb, nws yog ntuj thiab tuaj yeem siv rau hauv kev tsim cov khoom tu tawv nqaij.
KINTAI Certificate
Cim npe nrov: Tuam Tshoj betulin hmoov manufacturers, lwm tus neeg, Hoobkas
