Apigenin rau Pw tsaug zog

Thaum pw tsaug zog-kev pabcuam kev lag luam tseem raug kaw hauv kev sib tw hnyav nyob rau hauvmelatoninthiabGABA, puas muaj cov khoom xyaw uas ib txhij ua tau raws li peb qhov kev xav tau tseem ceeb ntawm kev ua tsis yog -hormonal cuam tshuam, muaj cov txheej txheem kev tshawb fawb pom tseeb, thiab muab cov lus pom zoo rau tus nqi? Nws yuav tsum tsis yog tsuas yog sedative uas knocks cov neeg siv tawm; es, nws yuav tsum yog cov khoom xyaw bioactive muaj peev xwm maj mam inducing physiological pw tsaug zog thaum muab anti-inflammatory thiab neuroprotective muaj peev xwm. Ntawm cov nroj tsuag ntau yam, apigenin ntsiag to tawm los ua ib feem peb ntawm - tiam pw tsaug zog - pab muaj nyob rau hauv R & D toj roob hauv pes ntawm kev lag luam.Yuav apigenin hmoov,tiv tauj pebntawminfo@kintaibio.com.

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Apigenin hmoovyog lub ntuj flavonoid, thiab ib tug tseem ceeb ntawm cov nroj tsuag polyphenol tsev neeg, dav pom nyob rau hauv celery, chamomile, parsley, thiab tej citrus txiv hmab txiv ntoo. Nws muaj npe nrov rau nws ntau yam - phiaj xwm lom neeg; tshwj xeeb hauv thaj tsam ntawm neuromodulation, apigenin xaiv khi rau benzodiazepine qhov chaw ntawmGABA-Areceptors nyob rau hauv lub hlwb, exerting me me sedative thiab anxiolytic teebmeem yam tsis ua rau lub siab ntev thiab kev vam khom txuam nrog ib txwm tshuaj benzodiazepine.

Tsis tas li ntawd,apigenin lojmuaj cov tshuaj tiv thaiv kab mob antioxidant thiab tiv thaiv - cov khoom inflammatory. Nws yog qhov tseeb qhov txiaj ntsig zoo dua, ua ke nrog kev so neural nrog kev tiv thaiv lub cev ntawm lub cev - uas ua rau apigenin tsis tsuas yog cov khoom cog lus rau covpw tsaug zog- pabkev ua lag luam tab sis kuj yog ib qho kev nrhiav heev - tom qab hla - dhau lub hnub qub molecule hauv kev txhim kho cov khoom noj khoom haus thiab cov khoom noj khoom haus zoo tshaj.

Los ntawm scientific foundations,apigenin ua's pw tsaug zog- txhim kho cov teebmeem tau zoo- tau tsim, thiab nws cov txheej txheem ntawm kev ua haujlwm muaj kev nyab xeeb dua thiab zoo dua li cov tsoospab pw tsaug zog. Qhov tseem ceeb, nws hla cov ntshav- lub hlwb teeb meem rau qhov zoo ntawm cov benzodiazepine site ntawm GABA-A receptors; ua haujlwm zoo li lub cev hloov pauv, nws ua tau zoo dampens hauv nruab nrab paj hlwb hyperexcitability, yog li txo qhov pib pw tsaug zog thiab txo qis kev tsaug zog thaum hmo ntuj, tsis muaj kev ntxhov siab ntau dhau los ntawm cov tshuaj siv tshuaj.

Tsis zoo li melatonin, uas feem ntau tswj cov circadian rhythms,apigenin hmoovkuj boasts muaj zog tiv thaiv -inflammatory thiab antioxidant zog. Los ntawm alleviating oxidative kev nyuaj siab thiab neuroinflammation ntawm ib qho tseem ceeb, nws pab daws cov insomnia theem nrab los ntawm kev ntxhov siab vim thiab lub cev nro. Kev tshawb fawb tsiaj ntau thiab kev soj ntsuam ua ntej qhia tau hais tias apigenin nce qhov feem ntawm kev pw tsaug zog thiab ua kom zoo rau kev pw tsaug zog zoo. Yog li ntawd, nws yog ib qho zoo tagnrho cov khoom xyaw rau siab - cov qauv kev pw tsaug zog zoo uas tseem ceeb uas tsis yog -hormonal cuam tshuam, tsis yog - cwj pwm - tsim cov khoom, thiab qhov tsis muaj cov nyhuv hangover hnub tom qab.

Kev pw tsaug zog- txhawb nqamechanism ntawm apigeninnyob rau hauv lub hauv paus ntawm lub paj hlwb lub braking system, lub GABAergic txoj kev. Tshwj xeeb, nws khi ncaj qha rau benzodiazepine allosteric site ntawm lub hlwb GABA-A receptor complex; ua zoo li ib tug maj mam, tej yam ntuj tso qhov tseem ceeb, nws txhim khu cov nyhuv inhibitory ntawmGABAkom calm overactive neurons thiab txo qhov nyuaj ntawm kev tsaug zog, tag nrho tsis ua rau yuam kev sedation los yog kev pheej hmoo ntawm dependency txuam nrog kws tshuaj.

Tshaj li qhov kev hloov kho receptor ncaj qha,apigenin uakuj dampens excitatory glutamatergic signaling thiab hla cov ntshav - hlwb teeb meem nrog yooj yim, kom ntseeg tau tias nws calming cawv mus txog lub hauv paus paj hlwb sai thiab zoo thaum tib lub sij hawm txo neuroinflammation thiab oxidative kev nyuaj siab los kho lub hlwb lub ntuj excitation-inhibition ntev.

Thaum tham txog covpw tsaug zog- txhawb nqa cov txiaj ntsig ntawm apigenin, nws qhov tshwj xeeb kom zoo dua yog nyob rau hauv yuav ua li cas nws ua raws li lub cev kev pw tsaug zog ntuj -pib txoj hauv kev es tsis yog yuam kom kaw lub wakefulness. Hloov chaw tsuas yog rub tus neeg siv tawm, nws maj mam txo qis qhov kev xav ntawm qhov pib los ntawm kev txhim kho lub hlwb rhiab heev rau nws tus kheej cov cim inhibitory, tso cai rau lub hlwb qaug zog kom yooj yim dua plam mus rau hauv kev sib sib zog nqus tob - pw tsaug zog xeev. Hauv cov txheej txheem, apigenin kuj tseem pab tswj cov hypothalamic -pituitary-adrenal (HPA) axis thiab buffers tawm tsam qhov txawv txav nocturnal cortisol secretion, qhov tseem ceeb tshwj xeeb tshaj yog rau cov neeg muaj kev ntxhov siab-inducedinsomnia. Thaum muaj ntau yam kev pab pw tsaug zog tsuas yog cov lus nug ntawm seb ib tus tuaj yeem pw tsaug zog, apigenin mus ib kauj ruam ntxiv los ntawm kev tsom mus rau kev pw tsaug zog zoo; nws pab txuas ntxiv cov theem tseem ceeb ntawm qhov tsis yog - nrawm qhov muag txav (NREM) pw tsaug zog, ua rau muaj kev pw tsaug zog zoo dua.

Raupw tsaug zog, cov lus pom zoonoj tshuaj apigeninfeem ntau poob rau hauv 50–100 mg - lub sijhawm ua haujlwm tau txais los ntawm cov kev tshawb fawb soj ntsuam tam sim no feem ntau thiab tsim cov tshuaj noj. Cov koob tshuaj tshwj xeeb yuav tsum tau hloov kho raws li cov extract lub purity thiab bioavailability; Piv txwv li, formulations siv liposomal encapsulation los yog kev sib txuas nrog piperine tuaj yeem txhim khu kev nqus, tso cai rau kev pom zoo ntawm cov koob tshuaj qis dua. Hais txog kev tswj hwm, nws raug nquahu kom noj cov tshuaj ntxiv 30 mus rau 60 feeb ua ntej yuav mus pw- nyob rau ntawm lub plab khoob lossis nrog me me ntawm cov rog noj qab haus huv, txhawm rau ua kom nws cov rog- cov khoom soluble thiab ua kom qhov pib tshwm sim.

Xav txog ob qho tib si circadian rhythms thiab kev nqus tau zoo, lub qhov rais zoo rau kev nojapigenin uayog kwv yees li 30 mus rau 60 feeb ua ntej yuav mus pw; Lub sijhawm no tso cai rau cov khoom muaj txiaj ntsig kom ncav cuag qhov siab tshaj plaws plasma concentration ib yam li lub cev npaj rau kev pw tsaug zog, ua kom yooj yim hloov pauv mus rau hauv tsaug zog. Raws liapigenin hmoovyog ib qho roj-soluble flavonoid, noj nrog me me ntawm cov roj noj qab haus huv, xws li ob peb txiv ntoo lossis yogurt me ntsis, tuaj yeem txhim kho nws cov kev sib cais thiab kev nqus tau zoo thaum tiv thaiv kev mob plab me me uas yuav tshwm sim ntawm lub plab khoob.

Kev noj nws tib lub sijhawm txhua hmo pab lub cev tsim kom muaj kev pw tsaug zog ruaj khov, yog li txhawb kev ua haujlwm tsis tu ncua ntawm lub moos lom neeg. Yog hais tias cov formulation suav nrog ceev - cov khoom xyaw xws limelatoninlos yogtheanine, lub sij hawm tuaj yeem hloov kho me ntsis mus rau 20-30 feeb ua ntej pw kom haum nrog lawv qhov pib profiles.

Peb muabapigenin hmoov raw cov ntaub ntawv xws li 50% mus rau 98% purity, haum rautshuaj ntsiavfilling, tsim los ua ke seamlessly rau hauv koj cov txheej txheem tsim tshwj xeeb. Txhawm rau kom ua raws li kev tswj hwm, peb muab cov ntaub ntawv qhia txog thib peb - tog xeem cov ntawv ceeb toom thiab Daim Ntawv Pov Thawj Kev Ntsuam Xyuas (COA) rau txhua pawg, lav tias peb cov khoom xyaw ua tau raws li cov qauv kev lag luam nruj tshaj plaws. Rov qab los ntawm kev muaj peev xwm R&D muaj peev xwm, peb muaj nyob rau hauv - kev pabcuam kev hloov kho qhov tob, suav nrog kev faib khoom raws li qhov loj me, cov qauv tsim ua ntej, thiab tus tswv saj- cov kev daws teeb meem npog, kom tau raws li koj cov kev xav tau tshwj xeeb.Tiv tauj pebntawminfo@kintaibio.com.

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